Physical dependence on zopiclone: case reports

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Physical dependence on zopiclone: case reports.

Over the past few decades there has been a reluctance to prescribe benzodiazepines for insomnia and anxiety, as evidence for dependence and withdrawal has accumulated. Alternative treatments have therefore been sought. Zopiclone, a cyclopyrrolone, is chemically unrelated to benzodiazepines but acts via the benzodiazepine/ãaminobutyric acid receptor complex. It is licensed for the short term tre...

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Abuse and dependence potential for the non-benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological data.

AIMS The non-benzodiazepine hypnotics zolpidem and zopiclone, which are indicated for short-term treatment of insomnia, were considered originally by physicians as almost devoid of abuse and dependence potential. Several recent publications, however, have suggested that both agents carry a significant risk of abuse. To substantiate and re-evaluate this situation, the world literature was review...

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CASE REPORTS Physical Therapy Management for Conversion Disorder: Case Series

Purpose: Patients with conversion disorder present with symptoms of sensory and motor dysfunction that are not explained by known physical disorders or pathophysiological mechanisms. Correct diagnosis and prompt, effective management of patients with this disorder is essential. Healthcare providers may be unaware of the important role of physical therapy in the management of patients with conve...

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INTERFERON INDUCED CARDIOMYOPATHY: CASE REPORTS

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Zopiclone use during pregnancy.

QUESTION One of my patients, whom I had treated with a 2-week course of zopiclone for insomnia, conceived while using the medication. She is concerned. How should I advise her? ANSWER Based on available, albeit limited, evidence, zopiclone does not appear to be a major human teratogen.

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ژورنال

عنوان ژورنال: BMJ

سال: 1998

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.316.7125.117